Recent Publications
2024
- Nanoparticle Retinoic Acid-Inducible Gene I Agonist for Cancer Immunotherapy.Wang-Bishop L, Wehbe M, Pastora LE, Yang J, Kimmel BR, Garland KM, Becker KW, Carson CS, Roth EW, Gibson-Corley KN, Ulkoski D, Krishnamurthy V, Fedorova O, Richmond A, Pyle AM, Wilson JT. ACS Nano. 2024 Apr 23; 2024 Apr 23. PMID: 38652829.
- Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons.Mohd Rafiq N, Fujise K, Rosenfeld MS, Xu P, De Camilli P. Proc Natl Acad Sci U S A. 2024 Apr 23; 2024 Apr 18. PMID: 38635628.
- Incidence and risk factors of pain crisis after hematopoietic cell transplantation for sickle cell disease.Krishnamurti L, Liang J, He Z, Deng Y, Nallagatla VR, Hamidi R, Flagg A, Shah N. Blood Adv. 2024 Apr 23. PMID: 38324722.
- Treatment of Myelodysplastic Syndromes for Older Patients: Current State of Science, Challenges, and Opportunities.Kewan T, Stahl M, Bewersdorf JP, Zeidan AM. Curr Hematol Malig Rep. 2024 Apr 18; 2024 Apr 18. PMID: 38632155.
- Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape.Boddu PC, Gupta AK, Roy R, De La Peña Avalos B, Olazabal-Herrero A, Neuenkirchen N, Zimmer JT, Chandhok NS, King D, Nannya Y, Ogawa S, Lin H, Simon MD, Dray E, Kupfer GM, Verma A, Neugebauer KM, Pillai MM. Mol Cell. 2024 Apr 18; 2024 Mar 22. PMID: 38521065.
- Answering Dr Lee about the future role of phenome.Abbott J, Abrao M, Al-Jefout M, Bedaiwy M, Benagiano G, Burns KA, Canis M, Carmona F, Chapron C, Critchley HOD, de Ziegler D, Falcone T, Fazleabas A, Ferrero S, Garcia-Velasco JA, Gargett C, Greaves E, Griffith LG, Guo SW, Habiba M, Harada T, Hull ML, Johnson NP, Kaufman Y, Issacson KB, Khan KN, Kim MR, Koninckx PA, Lessey BA, Martin D, Matsuzaki S, Mishra G, Osuga Y, Petraglia F, Popov A, Roman H, Romano A, Saunders P, Seckin T, Somigliana E, Taylor HS, Vercellini P, Vigano P. J Minim Invasive Gynecol. 2024 Apr 17; 2024 Apr 17. PMID: 38641049.
- Altered skin microbiome, inflammation, and JAK/STAT signaling in Southeast Asian ichthyosis patients.Ho M, Nguyen HN, Van Hoang M, Bui TTT, Vu BQ, Dinh THT, Vo HTM, Blaydon DC, Eldirany SA, Bunick CG, Bui CB. Hum Genomics. 2024 Apr 16; 2024 Apr 16. PMID: 38627868.
- UPF1 regulates mRNA stability by sensing poorly translated coding sequences.Musaev D, Abdelmessih M, Vejnar CE, Yartseva V, Weiss LA, Strayer EC, Takacs CM, Giraldez AJ. Cell Rep. 2024 Apr 15; 2024 Apr 15. PMID: 38625794.
- Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial.Parra ER, Zhang J, Duose DY, Gonzalez-Kozlova E, Redman MW, Chen H, Manyam GC, Kumar G, Zhang J, Song X, Lazcano R, Marques-Piubelli ML, Laberiano-Fernandez C, Rojas F, Zhang B, Taing L, Jhaveri A, Geisberg J, Altreuter J, Michor F, Provencher J, Yu J, Cerami E, Moravec R, Kannan K, Luthra R, Alatrash G, Huang HH, Xie H, Patel M, Nie K, Harris J, Argueta K, Lindsay J, Biswas R, Van Nostrand S, Kim-Schulze S, Gray JE, Herbst RS, Wistuba II, Gettinger S, Kelly K, Bazhenova L, Gnjatic S, Lee JJ, Zhang J, Haymaker C. Clin Cancer Res. 2024 Apr 15. PMID: 38277235.
- Mannose controls mesoderm specification and symmetry breaking in mouse gastruloids.Dingare C, Cao D, Yang JJ, Sozen B, Steventon B. Dev Cell. 2024 Apr 9; 2024 Apr 9. PMID: 38636516.
- DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells.Ren X, Liu Q, Zhou P, Zhou T, Wang D, Mei Q, Flavell RA, Liu Z, Li M, Pan W, Zhu S. Nat Commun. 2024 Apr 9; 2024 Apr 9. PMID: 38594251.
- Stem cell migration drives lung repair in living mice.Chioccioli M, Liu S, Magruder S, Tata A, Borriello L, McDonough JE, Konkimalla A, Kim SH, Nouws J, Gonzalez DG, Traub B, Ye X, Yang T, Entenberg DR, Krishnaswamy S, Hendry CE, Kaminski N, Tata PR, Sauler M. Dev Cell. 2024 Apr 8; 2024 Feb 19. PMID: 38377991.
- COVID-19 Vaccination in Patients with Inborn Errors of Immunity Reduces Hospitalization and Critical Care Needs Related to COVID-19: a USIDNET Report.McDonnell J, Cousins K, Younger MEM, Lane A, Abolhassani H, Abraham RS, Al-Tamemi S, Aldave-Becerra JC, Al-Faris EH, Alfaro-Murillo A, AlKhater SA, Alsaati N, Doss AMA, Anderson M, Angarola E, Ariue B, Arnold DE, Assa'ad AH, Aytekin C, Bank M, Bergerson JRE, Bleesing J, Boesing J, Bouso C, Brodszki N, Cabanillas D, Cady C, Callahan MA, Caorsi R, Carbone J, Carrabba M, Castagnoli R, Catanzaro JR, Chan S, Chandra S, Chapdelaine H, Chavoshzadeh Z, Chong HJ, Connors L, Consonni F, Correa-Jimenez O, Cunningham-Rundles C, D'Astous-Gauthier K, Delmonte OM, Demirdag YY, Deshpande DR, Diaz-Cabrera NM, Dimitriades VR, El-Owaidy R, ElGhazali G, Al-Hammadi S, Fabio G, Faure AS, Feng J, Fernandez JM, Fill L, Franco GR, Frenck RW, Fuleihan RL, Giardino G, Galant-Swafford J, Gambineri E, Garabedian EK, Geerlinks AV, Goudouris E, Grecco O, Pan-Hammarström Q, Khani HHK, Hammarström L, Hartog NL, Heimall J, Hernandez-Molina G, Horner CC, Hostoffer RW, Hristova N, Hsiao KC, Ivankovich-Escoto G, Jaber F, Jalil M, Jamee M, Jean T, Jeong S, Jhaveri D, Jordan MB, Joshi AY, Kalkat A, Kanarek HJ, Kellner ES, Khojah A, Khoury R, Kokron CM, Kumar A, Lecerf K, Lehman HK, Leiding JW, Lesmana H, Lim XR, Lopes JP, López AL, Tarquini L, Lundgren IS, Magnusson J, Marinho AKBB, Marseglia GL, Martone GM, Mechtler AG, Mendonca L, Milner JD, Mustillo PJ, Naderi AG, Naviglio S, Nell J, Niebur HB, Notarangelo L, Oleastro M, Ortega-López MC, Patel NR, Petrovic G, Pignata C, Porras O, Prince BT, Puck JM, Qamar N, Rabusin M, Raje N, Regairaz L, Risma KA, Ristagno EH, Routes J, Roxo-Junior P, Salemi N, Scalchunes C, Schuval SJ, Seneviratne SL, Shankar A, Sherkat R, Shin JJ, Siddiqi A, Signa S, Sobh A, Lima FMS, Stenehjem KK, Tam JS, Tang M, Barros MT, Verbsky J, Vergadi E, Voelker DH, Volpi S, Wall LA, Wang C, Williams KW, Wu EY, Wu SS, Zhou JJ, Cook A, Sullivan KE, Marsh R. J Clin Immunol. 2024 Apr 5; 2024 Apr 5. PMID: 38578389.
- Parasympathetic neurons derived from human pluripotent stem cells model human diseases and development.Wu HF, Saito-Diaz K, Huang CW, McAlpine JL, Seo DE, Magruder DS, Ishan M, Bergeron HC, Delaney WH, Santori FR, Krishnaswamy S, Hart GW, Chen YW, Hogan RJ, Liu HX, Ivanova NB, Zeltner N. Cell Stem Cell. 2024 Apr 4; 2024 Apr 4. PMID: 38608707.
- A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus.Singh AK, Allington G, Viviano S, McGee S, Kiziltug E, Ma S, Zhao S, Mekbib KY, Shohfi JP, Duy PQ, DeSpenza T Jr, Furey CG, Reeves BC, Smith H, Sousa AMM, Cherskov A, Allocco A, Nelson-Williams C, Haider S, Rizvi SRA, Alper SL, Sestan N, Shimelis H, Walsh LK, Lifton RP, Moreno-De-Luca A, Jin SC, Kruszka P, Deniz E, Kahle KT. Brain. 2024 Apr 4. PMID: 38128548.
- Reconstructing axial progenitor field dynamics in mouse stem cell-derived embryoids.Bolondi A, Law BK, Kretzmer H, Gassaloglu SI, Buschow R, Riemenschneider C, Yang D, Walther M, Veenvliet JV, Meissner A, Smith ZD, Chan MM. Dev Cell. 2024 Apr 3; 2024 Apr 3. PMID: 38579718.
- A brainstem-hypothalamus neuronal circuit reduces feeding upon heat exposure.Benevento M, Alpár A, Gundacker A, Afjehi L, Balueva K, Hevesi Z, Hanics J, Rehman S, Pollak DD, Lubec G, Wulff P, Prevot V, Horvath TL, Harkany T. Nature. 2024 Apr; 2024 Mar 27. PMID: 38538787.
- An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors.Zhang X, Song B, Carlino MJ, Li G, Ferchen K, Chen M, Thompson EN, Kain BN, Schnell D, Thakkar K, Kouril M, Jin K, Hay SB, Sen S, Bernardicius D, Ma S, Bennett SN, Croteau J, Salvatori O, Lye MH, Gillen AE, Jordan CT, Singh H, Krause DS, Salomonis N, Grimes HL. Nat Immunol. 2024 Apr; 2024 Mar 21. PMID: 38514887.
- Identifying an Early Neuropathological Mechanism in Schizophrenia With Brain Organoids.Kim J, Park IH. Biol Psychiatry. 2024 Apr 1. PMID: 38479977.
- HRAS-Mutant Cardiomyocyte Model of Multifocal Atrial Tachycardia.Rodríguez NA, Patel N, Dariolli R, Ng S, Aleman AG, Gong JQX, Lin HM, Rodríguez M, Josowitz R, Sol-Church K, Gripp KW, Lin X, Song SC, Fishman GI, Sobie EA, Gelb BD. Circ Arrhythm Electrophysiol. 2024 Apr; 2024 Feb 28. PMID: 38415356.
- Hypomethylating agents plus venetoclax compared with intensive induction chemotherapy regimens in molecularly defined secondary AML.Shimony S, Bewersdorf JP, Shallis RM, Liu Y, Schaefer EJ, Zeidan AM, Goldberg AD, Stein EM, Marcucci G, Lindsley RC, Chen EC, Ramos Perez J, Stein A, DeAngelo DJ, Neuberg DS, Stone RM, Ball B, Stahl M. Leukemia. 2024 Apr; 2024 Feb 20. PMID: 38378841.
- Current state of the epilepsy drug and device pipeline.Terman SW, Kirkpatrick L, Akiyama LF, Baajour W, Atilgan D, Dorotan MKC, Choi HW, French JA. Epilepsia. 2024 Apr; 2024 Feb 12. PMID: 38345387.
- Long-term outcomes after unrelated donor transplantation for severe sickle cell disease on the BMT CTN 0601 trial.Eapen M, Kou J, Andreansky M, Bhatia M, Brochstein J, Chaudhury S, Haight AE, Haines H, Jacobsohn D, Jaroscak J, Kasow KA, Krishnamurti L, Levine JE, Leung K, Margolis D, Yu LC, Horowitz MM, Kamani N, Walters MC, Shenoy S. Am J Hematol. 2024 Apr; 2024 Feb 11. PMID: 38343182.
- Combining physical & cognitive training with iPSC-derived dopaminergic neuron transplantation promotes graft integration & better functional outcome in parkinsonian marmosets.Daadi EW, Daadi ES, Oh T, Li M, Kim J, Daadi MM. Exp Neurol. 2024 Apr; 2024 Jan 23. PMID: 38272159.
- IL-10 dampens antitumor immunity and promotes liver metastasis via PD-L1 induction.Shiri AM, Zhang T, Bedke T, Zazara DE, Zhao L, Lücke J, Sabihi M, Fazio A, Zhang S, Tauriello DVF, Batlle E, Steglich B, Kempski J, Agalioti T, Nawrocki M, Xu Y, Riecken K, Liebold I, Brockmann L, Konczalla L, Bosurgi L, Mercanoglu B, Seeger P, Küsters N, Lykoudis PM, Heumann A, Arck PC, Fehse B, Busch P, Grotelüschen R, Mann O, Izbicki JR, Hackert T, Flavell RA, Gagliani N, Giannou AD, Huber S. J Hepatol. 2024 Apr; 2023 Dec 30. PMID: 38160941.
- Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Nat Biotechnol. 2024 Apr; 2023 Aug 3. PMID: 37537499.
- Single-cell atlas of the small intestine throughout the human lifespan demonstrates unique features of fetal immune cells.Gu W, Eke C, Gonzalez Santiago E, Olaloye O, Konnikova L. Mucosal Immunol. 2024 Mar 28; 2024 Mar 28. PMID: 38555026.
- Regional european genetic ancestry predicts type I interferon level and risk of severe viral infection.Nln I, Shum J, Ghodke-Puranik Y, Tipon R, Triese D, Amin S, Makol A, Osborn T, Chowdhary V, Thanarajasingam U, Wampler Muskardin TL, Oke V, Gunnarsson I, Zickert A, Zervou MI, Boumpas DT, Svenungsson E, Goulielmos GN, Niewold TB. QJM. 2024 Mar 26; 2024 Mar 26. PMID: 38530799.
- Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis.Luan Y, Hu J, Wang Q, Wang X, Li W, Qu R, Yang C, Rajendran BK, Zhou H, Liu P, Zhang N, Shi Y, Liu Y, Tang W, Lu J, Wu D. Cell Rep. 2024 Mar 26; 2024 Mar 8. PMID: 38461416.
- The genomic and evolutionary landscapes of anaplastic thyroid carcinoma.Zeng PYF, Prokopec SD, Lai SY, Pinto N, Chan-Seng-Yue MA, Clifton-Bligh R, Williams MD, Howlett CJ, Plantinga P, Cecchini MJ, Lam AK, Siddiqui I, Wang J, Sun RX, Watson JD, Korah R, Carling T, Agrawal N, Cipriani N, Ball D, Nelkin B, Rooper LM, Bishop JA, Garnis C, Berean K, Nicolson NG, Weinberger P, Henderson YC, Lalansingh CM, Tian M, Yamaguchi TN, Livingstone J, Salcedo A, Patel K, Vizeacoumar F, Datti A, Xi L, Nikiforov YE, Smallridge R, Copland JA, Marlow LA, Hyrcza MD, Delbridge L, Sidhu S, Sywak M, Robinson B, Fung K, Ghasemi F, Kwan K, MacNeil SD, Mendez A, Palma DA, Khan MI, Shaikh M, Ruicci KM, Wehrli B, Winquist E, Yoo J, Mymryk JS, Rocco JW, Wheeler D, Scherer S, Giordano TJ, Barrett JW, Faquin WC, Gill AJ, Clayman G, Boutros PC, Nichols AC. Cell Rep. 2024 Mar 26; 2024 Feb 26. PMID: 38412093.
- Genetic contribution to microglial activation in schizophrenia.Koskuvi M, Pörsti E, Hewitt T, Räsänen N, Wu YC, Trontti K, McQuade A, Kalyanaraman S, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Blurton-Jones M, Hovatta I, Lähteenvuo M, Rolova T, Lehtonen Š, Tiihonen J, Koistinaho J. Mol Psychiatry. 2024 Mar 22; 2024 Mar 22. PMID: 38519640.
- Intestinal tuft cell immune privilege enables norovirus persistence.Strine MS, Fagerberg E, Darcy PW, Barrón GM, Filler RB, Alfajaro MM, D'Angelo-Gavrish N, Wang F, Graziano VR, Menasché BL, Damo M, Wang YT, Howitt MR, Lee S, Joshi NS, Mucida D, Wilen CB. Sci Immunol. 2024 Mar 22; 2024 Mar 22. PMID: 38517952.
- Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma.Ang DA, Carter JM, Deka K, Tan JHL, Zhou J, Chen Q, Chng WJ, Harmston N, Li Y. Nat Commun. 2024 Mar 21; 2024 Mar 21. PMID: 38514625.
- piRNA generation is associated with the pioneer round of translation in stem cells.Allikka Parambil S, Li D, Zelko M, Poulet A, van Wolfswinkel JC. Nucleic Acids Res. 2024 Mar 21. PMID: 38142432.
- Dedifferentiated early postnatal lung myofibroblasts redifferentiate in adult disease.Chandran RR, Adams TS, Kabir I, Gallardo-Vara E, Kaminski N, Gomperts BN, Greif DM. Front Cell Dev Biol. 2024; 2024 Mar 20. PMID: 38572485.
- RORγt up-regulates RAG gene expression in DP thymocytes to expand the Tcra repertoire.Naik AK, Dauphars DJ, Corbett E, Simpson L, Schatz DG, Krangel MS. Sci Immunol. 2024 Mar 15; 2024 Mar 15. PMID: 38489350.
- Human iPSC-Based Model of COPD to Investigate Disease Mechanisms, Predict SARS-COV-2 Outcome, and Test Preventive Immunotherapy.Dagher R, Moldobaeva A, Gubbins E, Clark S, Madel Alfajaro M, Wilen CB, Hawkins F, Qu X, Chien Chiang C, Li Y, Clarke L, Ikeda Y, Brown C, Kolbeck R, Ma Q, Rojas M, Koff JL, Ghaedi M. Stem Cells. 2024 Mar 14. PMID: 38183264.
- Interpreting single-cell messages in normal and aberrant hematopoiesis with the Cell Marker Accordion.Busarello E, Biancon G, Lauria F, Ibnat Z, Ramirez C, Tomè G, Aass KR, VanOudenhove J, Standal T, Viero G, Halene S, Tebaldi T. bioRxiv. 2024 Mar 12; 2024 Mar 12. PMID: 38559181.
- Mitapivat-Associated Rib Fracture in a Hemolytic Anemia Patient.Abouelkheer Y, Ladel L, Boxer D, Shafique S. Cureus. 2024 Mar; 2024 Mar 6. PMID: 38586665.
- Author Correction: Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments.Janiszewska M, Tabassum DP, Castaño Z, Cristea S, Yamamoto KN, Kingston NL, Murphy KC, Shu S, Harper NW, Del Alcazar CG, Alečković M, Ekram MB, Cohen O, Kwak M, Qin Y, Laszewski T, Luoma A, Marusyk A, Wucherpfennig KW, Wagle N, Fan R, Michor F, McAllister SS, Polyak K. Nat Cell Biol. 2024 Mar 5; 2024 Mar 5. PMID: 38443568.
- Complementary and Inducible creER(T2) Mouse Models for Functional Evaluation of Endothelial Cell Subtypes in the Bone Marrow.Poulos MG, Ramalingam P, Winiarski A, Gutkin MC, Katsnelson L, Carter C, Pibouin-Fragner L, Eichmann A, Thomas JL, Miquerol L, Butler JM. Stem Cell Rev Rep. 2024 Mar 4; 2024 Mar 4. PMID: 38438768.
- The Epigenetic Evolution of Glioma Is Determined by the IDH1 Mutation Status and Treatment Regimen.Malta TM, Sabedot TS, Morosini NS, Datta I, Garofano L, Vallentgoed W, Varn FS, Aldape K, D'Angelo F, Bakas S, Barnholtz-Sloan JS, Gan HK, Hasanain M, Hau AC, Johnson KC, Cazacu S, deCarvalho AC, Khasraw M, Kocakavuk E, Kouwenhoven MCM, Migliozzi S, Niclou SP, Niers JM, Ormond DR, Paek SH, Reifenberger G, Sillevis Smitt PA, Smits M, Stead LF, van den Bent MJ, Van Meir EG, Walenkamp A, Weiss T, Weller M, Westerman BA, Ylstra B, Wesseling P, Lasorella A, French PJ, Poisson LM, Verhaak RGW, Iavarone A, Noushmehr H. Cancer Res. 2024 Mar 4. PMID: 38117484.
- Atypical pneumonia testing in transplant recipients.Feller F, Trubin P, Malinis M, Vogel JS, Merwede J, Peaper DR, Azar MM. Transpl Infect Dis. 2024 Mar 2; 2024 Mar 2. PMID: 38430482.
- Autophagy differentially regulates tissue tolerance of distinct target organs in graft-versus-host disease models.Oravecz-Wilson K, Lauder E, Taylor A, Maneix L, Van Nostrand JL, Sun Y, Li L, Zhao D, Liu C, Reddy P. J Clin Invest. 2024 Mar 1; 2024 Mar 1. PMID: 38426503.
- Circulating T cell specific extracellular vesicle profiles in cardiac allograft acute cellular rejection.Korutla L, Hoffman JR, Rostami S, Hu R, Korutla V, Markmann C, Mullan C, Sotolongo A, Habertheuer A, Romano C, Acker M, Sen S, Agarwal D, Jayaraman A, Li B, Davis ME, Naji A, Vallabhajosyula P. Am J Transplant. 2024 Mar; 2023 Oct 30. PMID: 38295008.
- in silico transcriptome dissection of neocortical excitatory neurogenesis via joint matrix decomposition and transfer learning.Sonthalia S, Li G, Blanco XM, Casella A, Liu J, Stein-O'Brien G, Caffo B, Adkins RS, Orvis J, Hertzano R, Mahurkar A, Gillis J, Werner J, Ma S, Micali N, Sestan N, Rakic P, Santpere G, Ament SA, Colantuoni C. bioRxiv. 2024 Feb 28; 2024 Feb 28. PMID: 38464021.
- Massively parallel disruption of enhancers active in human neural stem cells.Geller E, Noble MA, Morales M, Gockley J, Emera D, Uebbing S, Cotney JL, Noonan JP. Cell Rep. 2024 Feb 27; 2024 Jan 23. PMID: 38271204.
- The Wnt Co-Receptor PTK7/Otk and Its Homolog Otk-2 in Neurogenesis and Patterning.Tan QH, Otgonbaatar A, Kaur P, Ga AF, Harmston NP, Tolwinski NS. Cells. 2024 Feb 20; 2024 Feb 20. PMID: 38474329.
- Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways.Gurrea-Rubio M, Wang Q, Mills EA, Wu Q, Pitt D, Tsou PS, Fox DA, Mao-Draayer Y. Int J Mol Sci. 2024 Feb 20; 2024 Feb 20. PMID: 38473703.
- Activation of gp130 signaling in T cells drives T(H)17-mediated multi-organ autoimmunity.Baumgartner F, Bamopoulos SA, Faletti L, Hsiao HJ, Holz M, Gonzalez-Menendez I, Solé-Boldo L, Horne A, Gosavi S, Özerdem C, Singh N, Liebig S, Ramamoorthy S, Lehmann M, Demel U, Kühl AA, Wartewig T, Ruland J, Wunderlich FT, Schick M, Walther W, Rose-John S, Haas S, Quintanilla-Martinez L, Feske S, Ehl S, Glauben R, Keller U. Sci Signal. 2024 Feb 20; 2024 Feb 20. PMID: 38377177.
- Characterization of enhancer activity in early human neurodevelopment using Massively Parallel Reporter Assay (MPRA) and forebrain organoids.Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, Crawford GE, Ahituv N, Abyzov A, Vaccarino FM. Sci Rep. 2024 Feb 16; 2024 Feb 16. PMID: 38365907.
- Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model.Wang Y, Cho JW, Kastrunes G, Buck A, Razimbaud C, Culhane AC, Sun J, Braun DA, Choueiri TK, Wu CJ, Jones K, Nguyen QD, Zhu Z, Wei K, Zhu Q, Signoretti S, Freeman GJ, Hemberg M, Marasco WA. iScience. 2024 Feb 16; 2024 Jan 15. PMID: 38327771.
- Resilient wings, tangible impact: My journey from chrysalis to changemaker in STEM.Wilson JA. Cell. 2024 Feb 15. PMID: 38364786.
- Cell surface RNAs control neutrophil recruitment.Zhang N, Tang W, Torres L, Wang X, Ajaj Y, Zhu L, Luan Y, Zhou H, Wang Y, Zhang D, Kurbatov V, Khan SA, Kumar P, Hidalgo A, Wu D, Lu J. Cell. 2024 Feb 15; 2024 Jan 22. PMID: 38262409.
- Rehabilitation facilitates functional improvement following intravenous infusion of mesenchymal stem cells in the chronic phase of cerebral ischemia in rats.Yamashita T, Sasaki M, Sasaki Y, Nagahama H, Oka S, Kataoka-Sasaki Y, Ukai R, Yokoyama T, Kobayashi M, Kakizawa M, Kocsis JD, Honmou O. Brain Res. 2024 Feb 15; 2023 Dec 10. PMID: 38072373.
- Evidence for C-peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes.Latres E, Greenbaum CJ, Oyaski ML, Dayan CM, Colhoun HM, Lachin JM, Skyler JS, Rickels MR, Ahmed ST, Dutta S, Herold KC, Marinac M. Diabetes. 2024 Feb 13; 2024 Feb 13. PMID: 38349844.
- Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage.Arnhold V, Chang WY, Jansen SA, Thangavelu G, Calafiore M, Vinci P, Fu YY, Ito T, Takashima S, Egorova A, Kuttiyara J, Perlstein A, van Hoesel M, Liu C, Blazar BR, Lindemans CA, Hanash AM. J Clin Invest. 2024 Feb 13; 2024 Feb 13. PMID: 38349762.
- Fluoride transport in Arabidopsis thaliana plants is impaired in Fluoride EXporter (FEX) mutants.Tausta SL, Fontaine K, Hillmer AT, Strobel SA. Plant Mol Biol. 2024 Feb 11; 2024 Feb 11. PMID: 38342783.
- Real-World Survival, Healthcare Resource Utilization, and Costs Among U.S. Elderly Patients With Diffuse Large B-Cell Lymphoma (DLBCL) Treated With R-GemOx in the Relapsed/Refractory Setting.Garg M, Puckett J, Kamal-Bahl S, Raut M, Ryland KE, Doshi JA, Huntington SF. Clin Lymphoma Myeloma Leuk. 2024 Feb 9; 2024 Feb 9. PMID: 38433043.
- Spatially Exploring RNA Biology in Archival Formalin-Fixed Paraffin-Embedded Tissues.Bai Z, Zhang D, Gao Y, Tao B, Bao S, Enninful A, Zhang D, Su G, Tian X, Zhang N, Xiao Y, Liu Y, Gerstein M, Li M, Xing Y, Lu J, Xu ML, Fan R. bioRxiv. 2024 Feb 8; 2024 Feb 8. PMID: 38370833.
- IDHwt glioblastomas can be stratified by their transcriptional response to standard treatment, with implications for targeted therapy.Tanner G, Barrow R, Ajaib S, Al-Jabri M, Ahmed N, Pollock S, Finetti M, Rippaus N, Bruns AF, Syed K, Poulter JA, Matthews L, Hughes T, Wilson E, Johnson C, Varn FS, Brüning-Richardson A, Hogg C, Droop A, Gusnanto A, Care MA, Cutillo L, Westhead DR, Short SC, Jenkinson MD, Brodbelt A, Chakrabarty A, Ismail A, Verhaak RGW, Stead LF. Genome Biol. 2024 Feb 7; 2024 Feb 7. PMID: 38326875.
- Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1.Tejwani L, Ravindra NG, Lee C, Cheng Y, Nguyen B, Luttik K, Ni L, Zhang S, Morrison LM, Gionco J, Xiang Y, Yoon J, Ro H, Haidery F, Grijalva RM, Bae E, Kim K, Martuscello RT, Orr HT, Zoghbi HY, McLoughlin HS, Ranum LPW, Shakkottai VG, Faust PL, Wang S, van Dijk D, Lim J. Neuron. 2024 Feb 7; 2023 Nov 27. PMID: 38016472.
- The conserved RNA-binding protein Imp is required for the specification and function of olfactory navigation circuitry in Drosophila.Hamid A, Gattuso H, Caglar AN, Pillai M, Steele T, Gonzalez A, Nagel K, Syed MH. Curr Biol. 2024 Feb 5; 2024 Jan 4. PMID: 38181792.
- Autonomous transposons tune their sequences to ensure somatic suppression.Ilık İA, Glažar P, Tse K, Brändl B, Meierhofer D, Müller FJ, Smith ZD, Aktaş T. Nature. 2024 Feb; 2024 Feb 14. PMID: 38355802.
- Modulation of canonical Wnt signaling regulates peribiliary mesenchymal identity during homeostasis and injury.Singh S, Budiman T, Redmond D, Gupta V. Hepatol Commun. 2024 Feb 1; 2024 Jan 22. PMID: 38251878.
- Insertion of a FLAG-tag sequence at the end of exon 9 of the TBX5 gene in three induced pluripotent stem cell lines (DHMi004-A-4, DHMi004-A-5, DHMi004-A-6) by CRISPR/Cas9 technology.Lahm H, Singh NK, Gottmann I, Doppler SA, Dzilic E, Preisler H, Schneider S, Lange R, Krane M, Dreßen M. Stem Cell Res. 2024 Feb; 2023 Nov 25. PMID: 38100916.
- Modelling post-implantation human development to yolk sac blood emergence.Hislop J, Song Q, Keshavarz F K, Alavi A, Schoenberger R, LeGraw R, Velazquez JJ, Mokhtari T, Taheri MN, Rytel M, Chuva de Sousa Lopes SM, Watkins S, Stolz D, Kiani S, Sozen B, Bar-Joseph Z, Ebrahimkhani MR. Nature. 2024 Feb; 2023 Dec 13. PMID: 38092041.
- AAV-mediated delivery of a Sleeping Beauty transposon and an mRNA-encoded transposase for the engineering of therapeutic immune cells.Ye L, Lam SZ, Yang L, Suzuki K, Zou Y, Lin Q, Zhang Y, Clark P, Peng L, Chen S. Nat Biomed Eng. 2024 Feb; 2023 Jul 10. PMID: 37430157.
- The cholesterol biosynthesis enzyme FAXDC2 couples Wnt/β-catenin to RTK/MAPK signaling.Madan B, Wadia SR, Patnaik S, Harmston N, Tan E, Tan IBH, Nes WD, Petretto E, Virshup DM. J Clin Invest. 2024 Jan 23; 2024 Jan 23. PMID: 38488003.
- Regulation of nuclear transcription by mitochondrial RNA in endothelial cells.Sriram K, Qi Z, Yuan D, Malhi NK, Liu X, Calandrelli R, Luo Y, Tapia A, Jin S, Shi J, Salas M, Dang R, Armstrong B, Priceman SJ, Wang PH, Liao J, Natarajan R, Zhong S, Bouman Chen Z. Elife. 2024 Jan 22; 2024 Jan 22. PMID: 38251974.
- Presenilin-1 in smooth muscle cells facilitates hypermuscularization in elastin aortopathy.Saito J, Dave JM, Lau FD, Greif DM. iScience. 2024 Jan 19; 2023 Dec 13. PMID: 38226162.
- Antitumor efficacy of a sequence-specific DNA-targeted γPNA-based c-Myc inhibitor.Malik S, Pradeep SP, Kumar V, Xiao Y, Deng Y, Fan R, Vasquez JC, Singh V, Bahal R. Cell Rep Med. 2024 Jan 16; 2024 Jan 5. PMID: 38183981.
- Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy.Verma N, Renauer PA, Dong C, Xin S, Lin Q, Zhang F, Glazer PM, Chen S. bioRxiv. 2024 Jan 15; 2024 Jan 15. PMID: 38293095.
- Transitions in development - an interview with Berna Sozen.Development. 2024 Jan 15; 2024 Jan 17. PMID: 38231011.
- Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders.Ma Y, Bendl J, Hartley BJ, Fullard JF, Abdelaal R, Ho SM, Kosoy R, Gochman P, Rapoport J, Hoffman GE, Brennand KJ, Roussos P. Biol Psychiatry. 2024 Jan 15; 2023 Jul 14. PMID: 37454787.
- Organ Boundary Circuits Regulate Sox9+ Alveolar Tuft Cells During Post-Pneumonectomy Lung Regeneration.Obata T, Mizoguchi S, Greaney AM, Adams T, Yuan Y, Edelstein S, Leiby KL, Rivero R, Wang N, Kim H, Yang J, Schupp JC, Stitelman D, Tsuchiya T, Levchenko A, Kaminski N, Niklason LE, Brickman Raredon MS. bioRxiv. 2024 Jan 8; 2024 Jan 8. PMID: 38260691.
- Dysregulation of alternative splicing in spinocerebellar ataxia type 1.Olmos V, Thompson EN, Gogia N, Luttik K, Veeranki V, Ni L, Sim S, Chen K, Krause DS, Lim J. Hum Mol Genet. 2024 Jan 7. PMID: 37802886.
- Paneth-like cells produced from OLFM4(+) stem cells support OLFM4(+) stem cell growth in advanced colorectal cancer.Sakahara M, Okamoto T, Srivastava U, Natsume Y, Yamanaka H, Suzuki Y, Obama K, Nagayama S, Yao R. Commun Biol. 2024 Jan 5; 2024 Jan 5. PMID: 38182890.
- Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies.Liu Q, Zhang J, Guo C, Wang M, Wang C, Yan Y, Sun L, Wang D, Zhang L, Yu H, Hou L, Wu C, Zhu Y, Jiang G, Zhu H, Zhou Y, Fang S, Zhang T, Hu L, Li J, Liu Y, Zhang H, Zhang B, Ding L, Robles AI, Rodriguez H, Gao D, Ji H, Zhou H, Zhang P. Cell. 2024 Jan 4. PMID: 38181741.
- Allogeneic transplantation and cellular therapies in cutaneous T-cell lymphoma.Goyal A, Foss F. Expert Rev Anticancer Ther. 2024 Jan-Feb; 2024 Feb 12. PMID: 38224371.
- Extent of resection for low-grade gliomas - Prognostic or therapeutic?Kinslow CJ, Garton ALA, Rae AI, Kocakavuk E, McKhann GM, Cheng SK, Sisti MB, Bruce JN, Wang TJC. Clin Neurol Neurosurg. 2024 Jan; 2024 Jan 9. PMID: 38219356.
- Immune Control in Repeated Babesia microti Infection in a Patient With B-Cell Deficiency.Little JS, Oakley MS, Thorner AR, Johnston D, Majam V, Liakos AD, Novack LA, Zheng H, Meredith S, Chou CK, Newton BR, Soiffer RJ, Krause PJ, Baden LR, Kumar S. Open Forum Infect Dis. 2024 Jan; 2023 Nov 13. PMID: 38213635.
- Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP.Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Nature. 2024 Jan. PMID: 38168624.
- 3D hepatic organoid production from human pluripotent stem cells.Jin ZL, Xu K, Kim J, Guo H, Yao X, Xu YN, Li YH, Ryu D, Kim KP, Hong K, Kim YJ, Wang L, Cao Q, Kim KH, Kim NH, Han DW. Differentiation. 2024 Jan-Feb; 2023 Dec 12. PMID: 38104501.
- Sabatolimab plus hypomethylating agents in previously untreated patients with higher-risk myelodysplastic syndromes (STIMULUS-MDS1): a randomised, double-blind, placebo-controlled, phase 2 trial.Zeidan AM, Ando K, Rauzy O, Turgut M, Wang MC, Cairoli R, Hou HA, Kwong YL, Arnan M, Meers S, Pullarkat V, Santini V, Malek K, Kiertsman F, Niolat J, Ramos PM, Menssen HD, Fenaux P, Miyazaki Y, Platzbecker U. Lancet Haematol. 2024 Jan; 2023 Dec 5. PMID: 38065203.
- Identification of constrained sequence elements across 239 primate genomes.Kuderna LFK, Ulirsch JC, Rashid S, Ameen M, Sundaram L, Hickey G, Cox AJ, Gao H, Kumar A, Aguet F, Christmas MJ, Clawson H, Haeussler M, Janiak MC, Kuhlwilm M, Orkin JD, Bataillon T, Manu S, Valenzuela A, Bergman J, Rouselle M, Silva FE, Agueda L, Blanc J, Gut M, de Vries D, Goodhead I, Harris RA, Raveendran M, Jensen A, Chuma IS, Horvath JE, Hvilsom C, Juan D, Frandsen P, Schraiber JG, de Melo FR, Bertuol F, Byrne H, Sampaio I, Farias I, Valsecchi J, Messias M, da Silva MNF, Trivedi M, Rossi R, Hrbek T, Andriaholinirina N, Rabarivola CJ, Zaramody A, Jolly CJ, Phillips-Conroy J, Wilkerson G, Abee C, Simmons JH, Fernandez-Duque E, Kanthaswamy S, Shiferaw F, Wu D, Zhou L, Shao Y, Zhang G, Keyyu JD, Knauf S, Le MD, Lizano E, Merker S, Navarro A, Nadler T, Khor CC, Lee J, Tan P, Lim WK, Kitchener AC, Zinner D, Gut I, Melin AD, Guschanski K, Schierup MH, Beck RMD, Karakikes I, Wang KC, Umapathy G, Roos C, Boubli JP, Siepel A, Kundaje A, Paten B, Lindblad-Toh K, Rogers J, Marques Bonet T, Farh KK. Nature. 2024 Jan; 2023 Nov 29. PMID: 38030727.
- Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways.Papoin J, Yan H, Leduc M, Le Gall M, Narla A, Palis J, Steiner LA, Gallagher PG, Hillyer CD, Gautier EF, Mohandas N, Blanc L. Am J Hematol. 2024 Jan; 2023 Nov 6. PMID: 37929634.
- Post-transplantation cyclophosphamide is associated with increased bacterial infections.Ustun C, Chen M, Kim S, Auletta JJ, Batista MV, Battiwalla M, Cerny J, Gowda L, Hill JA, Liu H, Munshi PN, Nathan S, Seftel MD, Wingard JR, Chemaly RF, Dandoy CE, Perales MA, Riches M, Papanicolaou GA. Bone Marrow Transplant. 2024 Jan; 2023 Oct 31. PMID: 37903992.
- Allogeneic stem cell transplant for treatment of mycosis fungoides and Sezary syndrome: a systematic review and meta-analysis.Goyal A, O'Leary D, Foss F. Bone Marrow Transplant. 2024 Jan; 2023 Oct 18. PMID: 37853164.
- Safety of ovarian cryopreservation and transplantation in patients with acute leukemia: a case series.Sönmezer M, Şükür YE, Saçıntı KG, Özkavukçu S, Kankaya D, Atabekoğlu CS, Cengiz Seval G, Oktay KH. Am J Obstet Gynecol. 2024 Jan; 2023 Sep 2. PMID: 37666382.
- Bioinformatics identifies predictors of arteriovenous fistula maturation.Liu J, Zhang D, Brahmandam A, Matsubara Y, Gao M, Tian J, Liu B, Shu C, Dardik A. J Vasc Access. 2024 Jan; 2022 Jun 10. PMID: 35686495.
2023
- Evidence for Functional Roles of MicroRNAs in Lineage Specification During Mouse and Human Preimplantation Development.Biondic S, Petropoulos S. Yale J Biol Med. 2023 Dec; 2023 Dec 29. PMID: 38161584.
- The Molecular Mechanisms Involved in the Hypertrophic Scars Post-Burn Injury.Pradhan M, Pethe P. Yale J Biol Med. 2023 Dec; 2023 Dec 29. PMID: 38161582.
- Enhancing Our Understanding of Cell Types, Differentiation, and Disease Through Enhancers: An Interview with César Daniel Meléndez-Ramírez, MS.Abu-Shamma R. Yale J Biol Med. 2023 Dec; 2023 Dec 29. PMID: 38161574.
- Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53.Lee JD, Menasche BL, Mavrikaki M, Uyemura MM, Hong SM, Kozlova N, Wei J, Alfajaro MM, Filler RB, Müller A, Saxena T, Posey RR, Cheung P, Muranen T, Heng YJ, Paulo JA, Wilen CB, Slack FJ. Cell Rep. 2023 Dec 26; 2023 Nov 21. PMID: 37991919.
- Precise Therapeutic Targeting of Distinct NRXN1(+/-) Mutations.Fernando MB, Fan Y, Zhang Y, Kammourh S, Murphy AN, Ghorbani S, Onatzevitch R, Pero A, Padilla C, Flaherty EK, Prytkova IK, Cao L, Williams S, Fang G, Slesinger PA, Brennand KJ. bioRxiv. 2023 Dec 23; 2023 Dec 23. PMID: 37961635.
- Genome Engineering for Next-Generation Cellular Immunotherapies.Park JJ, Lee KAV, Lam SZ, Tang K, Chen S. Biochemistry. 2023 Dec 19; 2022 Aug 5. PMID: 35930700.
- Macrophages control pathological interferon responses during viral respiratory infection.Hoagland DA, Rodríguez-Morales P, Mann AO, Yu S, Lai A, Vazquez AB, Pope SD, Lim J, Li S, Zhang X, Li MO, Medzhitov R, Franklin RA. bioRxiv. 2023 Dec 17; 2023 Dec 17. PMID: 38168230.
- Diencephalic organoids - A key to unraveling development, connectivity, and pathology of the human diencephalon.Kiral FR, Choe M, Park IH. Front Cell Neurosci. 2023; 2023 Dec 7. PMID: 38130869.
- Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses.Ramos Zapatero M, Tong A, Opzoomer JW, O'Sullivan R, Cardoso Rodriguez F, Sufi J, Vlckova P, Nattress C, Qin X, Claus J, Hochhauser D, Krishnaswamy S, Tape CJ. Cell. 2023 Dec 7. PMID: 38065081.